Idiopathic pulmonary haemosiderosis: diagnosis by gastric lavage

نویسنده

  • Ashim Bhuyan
چکیده

Introduction Idiopathic pulmonary haemosiderosis (IPH) is a rare disorder of unknown etiology characterised by iron deficiency anaemia, recurrent or chronic pulmonary symptoms, such as cough and haemoptysis, and diffuse pulmonary infiltrates.1 The incidence is reported from 0.24 to 1.23 cases per million selected populations.2 It affects paediatric patients in approximately 80% of cases with equal gender incidence.3 The presence of iron or haemosiderin in macrophages obtained in gastric or bronchoalveolar lavage is considered crucial in the diagnosis of the cinical syndrome of haemosiderosis.4

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Pitfalls in the diagnosis of idiopathic pulmonary haemosiderosis.

Idiopathic pulmonary haemosiderosis is a very rare but devastating disorder. Diagnosis is sometimes difficult and the clinical course exceedingly variable, as illustrated by this report of a girl, aged 2 years 4 months, with severe iron deficiency anaemia. There was no response to iron therapy and transfusions. Sustained and striking reticulocytosis associated with low haptoglobin mimicked haem...

متن کامل

Idiopathic pulmonary haemosiderosis revisited.

Idiopathic pulmonary haemosiderosis is a rare cause of diffuse alveolar haemorrhage of unknown aetiology. It occurs most frequently in children, has a variable natural history with repetitive episodes of diffuse alveolar haemorrhage, and has been reported to have a high mortality. Many patients develop iron deficiency anaemia secondary to deposition of haemosiderin iron in the alveoli. Examinat...

متن کامل

Bronchoalveolar lavage findings in a young adult with idiopathic pulmonary haemosiderosis and coeliac disease.

Idiopathic pulmonary haemosiderosis is a rare disease of unknown autoimmune aetiology, mainly affecting children and adolescents. A variety of coexisting autoimmune diseases have been described, including coeliac disease. We describe the case of a man, aged 19 yrs, presenting with a one year history of recurrent haemoptysis. Gluten and gliadin antibodies were positive, and the jejunal biopsy re...

متن کامل

Case report of idiopathic pulmonary haemosiderosis in a child with recurrent chest infections.

Idiopathic pulmonary haemosiderosis (IPH) is a rare condition that usually presents as a triad of haemoptysis, iron deficiency anaemia and pulmonary infiltrates. We report a case of IPH diagnosed in a 7 year old boy who had recurrent hospital admissions with severe chest infections and haemoptysis from his first few months of life. He was found to have microcytic hypochromic anaemia, diffuse in...

متن کامل

Idiopathic pulmonary haemosiderosis in an adult.

We report a very, rare case of idiopathic pulmonary haemosiderosis (IPH) occurring in a 68 yr old patient. Following alveolar haemorrhage onset, the diagnosis was obtained by a process of elimination, after clinical, endoscopic, cytohistological and laboratory investigations. The immunoglobulin G directed against myeloperoxidase antigen (C-ANCA), which was detected, can be regarded as indicativ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013